High blood pressure, abnormal triglyceride or cholesterol levels, increased blood sugar levels, and excess fat deposition around the waist are specific metabolic syndrome that can potentially increase the chances of type 2 diabetes, heart disease, and stroke. As per the latest study published in the Neurology journal, there is a correlation between increased chances of recurrent stroke and all-cause mortality and metabolic syndrome.
The author Li T, of China's Fourth Military Medical University, states that there are conflicting results on whether there is an increased risk of a second stroke and mortality due to metabolic syndrome, which is associated with increased risk of the first incident of stroke; therefore all available researches were analyzed by Li T et al. The results of this research may allow patients with metabolic syndrome and clinicians to understand whether there is a requirement for risk screening for recurrent stroke or not.
The meta-analysis included the results of six studies with a total of 11,000 participants with a follow-up duration of five years. In the follow-up duration, 1250 patients had a second incident of stroke. Therefore, the analysis showed that individuals with metabolic syndrome had a 46% increased likelihood of experiencing the second stroke than individuals without the syndrome.
Additionally, it was observed that the increased risk of the second stroke was related to independent components of metabolic syndromes, such as low levels of good cholesterol and a combination of two or more components. However, increased blood pressure, increased blood sugar levels, and excess fat deposition around the waist were not independently associated with the risk of the second stroke.
On the other hand, for risk of mortality, eight studies were combined, including 51,613 people with a follow-up duration of five years. The death of 4,210 people was recorded in that duration. It was noted that patients with metabolic syndrome had 27% increased chances of mortality than individuals without the syndrome.
Metabolic syndrome is tied to second stroke and death. Thus, lifestyle modification, exercise, and medication should be advised in such patients as prevention to decrease the risk of second stroke and death.