Transcatheter aortic valve replacement (TAVR) as an alternative to surgical aortic valve replacement (SAVR) has profoundly changed the management of patients with aortic valve stenosis (AS). Large unbiased nationwide data regarding TAVR implementation, impact on SAVR and their respective outcomes are scarce.

Based on a French administrative hospital-discharge database, we collected data on all consecutive aortic valve replacements (AVRs) performed in France for AS between 2007 and 2019 [106 253 isolated SAVR (49%), 46 514 combined SAVR (21%), and 65 651 TAVR (30%)]. The number of AVR linearly increased between 2007 and 2019 due to a marked increase in TAVR, while SAVR increased up to 2013 and then declined. The Charlson index decreased linearly for TAVR, but in two steps for SAVR . In-hospital mortality rates of both SAVR and TAVR declined and were similar or lower for TAVR than for isolated SAVR in patients 75 years or above in the last 3 years. Complication rates of TAVR also declined but permanent pacemaker rates remained high and length of stay substantial.

The number of AVR has doubled in a decade and TAVR has become the dominant form of AVR in 2018. The improvement in patient profiles seems to have anticipated the demonstrated benefit of TAVR in intermediate and low-risk patients. In patients 75 years or older, TAVR should be considered as the first option. We also highlight two important areas for improvement, the high permanent pacemaker rates, and the long length of stay even in the contemporary era. Our results may have major implications for clinical practice and policymakers.

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Source

https://academic.oup.com/eurheartj/advance-article-abstract/doi/10.1093/eurheartj/ehab773/6439994?redirectedFrom=fulltext

Tags

Disease Condition ,Therapeutic Modality ,Valvular heart disease,Cardiovascular Surgery,Interventional Cardiology,Aortic Stenosis,TCVS_others,Percutaneous Coronary Intervention,Trans catheter Therapy