The Zio XT wearable ECG patch yielded an Afib detection rate of 5.3% by 6 months, compared with 0.5% achieved through standard care (RR 11.2, 95% CI 2.7-47.1), according to researchers led by David Gladstone, MD, PhD, of Sunnybrook Research Institute at the University of Toronto.
SCREEN-AF participants were 856 older community-dwelling individuals with hypertension and no known Afib who were judged to be at moderate or high risk for stroke. Mean age was 80.0 years, and 56.9% of participants were women.
The trial was conducted in Canada and Germany at 48 primary care practices in 2015-2019.
Results were less promising for intermittent oscillometric screening. A deluge of false positives and missed Afib episodes gave this form of screening a sensitivity of 35.0%, specificity of 81.0%, positive predictive value of 8.9%, and negative predictive value of 95.9%.